Nanoscale radiotherapy with hafnium oxide nanoparticles

In this study, hafnium oxide nanoparticles were designed that concentrate in tumor cells to achieve intracellular high-energy dose deposit. Materials & methods: Conventional methods were used, implemented in different ways, to explore interactions of these high-atomic-number nanoparticles and ionizing radiation with biological systems.

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PD-L1 aptamer-functionalized degradable hafnium …

PD-L1 aptamer-functionalized degradable hafnium oxide nanoparticles for near infrared-II diagnostic imaging and radiosensitization Min Wei1,2,3,4,5, Xiao Shen1,2,3,4,5, Xueqi Fan1,2,3,4,5, Jiwei Li6 and Jingwen Bai1,2,3,4,5,7* 1Cancer Center and Department of Breast and Thyroid Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen …

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In Situ Gas Phase Diagnostics for Hafnium Oxide

This report will describe the status of a project to develop in situ diagnostics for hafnium oxide ALD processes. The focus is on an examination of the utility of Fourier transform infrared spectroscopy and diode laser spectroscopy for optimizing deposition conditions, rather than simply monitoring precursor delivery.

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(PDF) Silicon Nanowires with High-k Hafnium Oxide …

Silicon Nanowires with High-k Hafnium Oxide Dielectrics for Sensitive Detection of Small Nucleic Acid Oligomers. ... Such diagnostic devices have the potential to provide critical patient information more rapidly at cheaper costs than instruments in centralized lab facilities, reducing the turnaround time for results in critical care situations ...

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Silicon Nanowires with High-k Hafnium Oxide Dielectrics …

In this paper, we describe a process for fabricating stable HfO2 dielectric-based silicon nanowires for biosensing applications. Here we demonstrate sensing of single-stranded DNA analogues …

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Advances of hafnium based nanomaterials for cancer …

Advances of hafnium based nanomaterials for cancer theranostics Jiayi Wang1†, Jiahua Pan1†, Yijun Tang2, Jingqi Chen1, Xiaochen Fei1, Wei Xue1* and Xueliang Liu1* 1Department of Urology and Institute of Molecular Medicine (IMM), Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, 2Department of Endocrinology and Metabolism,

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Effect of oxygen plasma treatment on the properties of ALD hafnium …

The dominant trap in hafnium oxide is an oxygen vacancy [7, 9]. Thus, to reduce gate leakage currents, it is important to reduce the concentration of oxygen vacancies in hafnium oxide films, but at the same time maintain their amorphism. To stabilize the properties of hafnium oxide in the gate dielectric, annealing is used at different ...

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In Situ Gas Phase Diagnostics for Hafnium Oxide Atomic …

This report describes the status of a project to develop in situ diagnostics for hafnium oxide ALD processes. The focus is on an examination of the utility of Fourier transform …

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HfO2 99.9% 1.5-3.5mm 500g

Discover everything you need to know about HfO2 99.9% 1.5-3.5mm 500g - 0707542-00500G by Umicore Metal Deposition Solutions.

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In Situ Gas Phase Diagnostics for Hafnium Oxide Atomic …

This report will describe the status of a project to develop in situ diagnostics for ALD processes. The current emphasis of this project is on gas-phase optical sensors.

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Optical and X-ray attenuation properties of hafnium …

In this study, we report hafnium oxide nanoparticles (HfO2 NPs) designed as a CT contrast agent for an emerging imaging technology named spectral photon counting computed tomography …

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Nanoparticle Diagnostics and Theranostics in the Clinic

NBTXR3 is also in clinical trials for the treatment of other types of cancer (Supplemental Table 2). Hafnium is a high-atomic-number element and (like gadolinium) has a strong photoelectric absorption coefficient, which causes hafnium oxide nanoparticles to display both strong radiosensitizing properties and strong CT contrast.

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Hafnium oxide nanoparticles: toward an in vitro predictive …

Preliminary results suggest a predictable in vitro biological effect of NBTXR3 nanoparticles exposed to ionizing radiation. BackgroundHafnium oxide, NBTXR3 nanoparticles were designed for high dose energy deposition within cancer cells when exposed to ionizing radiation. The purpose of this study was to assess the possibility of predicting in vitro the …

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PD-L1 aptamer-functionalized degradable hafnium oxide …

PD-L1 aptamer-functionalized degradable hafnium oxide nanoparticles for near infrared-II diagnostic imaging and radiosensitization. Min Wei. Min Wei. 1 Cancer Center and Department of Breast and ... Hafnium oxide nanoparticles have been provided in sarcomas, pancreatic ductal adenocarcinoma, and squamous cell carcinoma with a high safety ...

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Growth characteristics and physicochemical properties of …

Well defined nanostructures of doped or undoped HfO 2 with unique physicochemical properties are crucial for applications in electronics, optoelectronics, sensors, and biomaterials. In this context, we have studied the fabrication of nanoporous anodic hafnium oxide (AHO) thin layers in ethylene glycol-based electrolytes containing NH 4 F. Although …

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Atomic Layer Deposition of Lanthanum Stabilized Amorphous Hafnium Oxide …

Hafnium dioxide deposited on n-Si(100) by atomic layer deposition (ALD) was incorporated with La2O3 to stabilize the amorphous phase during high-temperature annealing. The incorporation of La was achieved by depositing HfO2 and La2O3 in different ALD cycles that likely produced a HfO2−HfLaxOy periodic structure. X-ray photoelectron spectroscopy …

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Hafnium(IV) oxide powder, 98 1

Hafnium(IV) oxide: Utilized predominantly in the semiconductor industry, Hafnium(IV) oxide offers excellent thermal and chemical stability, which makes it suitable as a high-k gate dielectric material in metal-oxide-semiconductor (MOS) devices. Its application has become increasingly important with the miniaturization of electronic components, aiding in the enhancement of …

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Modeling the influence of the duration of water vapor pulses …

Hafnium oxide is emerging as a leader in modern nanoelectronics materials [1,2], which is because of its important properties. This material claims to replace silicon oxide in field-effect transistors [3,4] and is used in capacitors [2,5], having a good dielectric constant.

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Evaluation of hafnium oxide nanoparticles imaging …

This research aimed to compare the quantitative imaging attributes of synthesized hafnium oxide nanoparticles (NPs) derived from UiO-66-NH2(Hf) and two gadolinium- and iodine-based clinical contrast agents (CAs) using cylindrical phantom. Aqueous solutions of the studied CAs, containing 2.5, 5, and 10 mg/mL of HfO2NPs, gadolinium, and iodine, were prepared. …

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Use of hafnium(IV) oxide in biosensors

The interaction of hafnium oxide (HfO2) nanoparticles (NPs) with X-ray and mid-infrared radiation was investigated to assess the potential as a multifunctional diagnostic probe for X-ray...

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Silicon Nanowires with High-k Hafnium Oxide Dielectrics for …

Silicon Nanowires with High-k Hafnium Oxide Dielectrics for Sensitive Detection of Small Nucleic Acid Oligomers. ... (POC) medical diagnostics. Unfortunately, a number of performance issues such as gate leakage and current instability due to fluid contact, have prevented widespread adoption of the technology for routine use.

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PD-L1 aptamer-functionalized degradable hafnium oxide

Download Citation | PD-L1 aptamer-functionalized degradable hafnium oxide nanoparticles for near infrared-II diagnostic imaging and radiosensitization | Immune checkpoint blockade is now ...

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Crystal and Electronic Structure of Oxygen …

Hafnium oxide is an outstanding candidate for next-generation nonvolatile memory solutions such as OxRAM (oxide-based resistive memory) and FeRAM (ferroelectric random access memory). A key parameter for OxRAM is the …

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Silicon Nanowires with High-k Hafnium Oxide Dielectrics for Sensitive

In order to mitigate stability issues of SiNW biosensors in fluid environments, Dorvel et al. [128] proposed the use of the high-k dielectric hafnium oxide (HfO 2 ) instead of silicon oxide as a ...

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Hafnium Oxide Nanostructured Thin Films: …

In the frame of the nanoarchitectonic concept, the objective of this study was to develop simple and easy methods to ensure the preparation of polymorphic HfO2 thin film materials (<200 nm) having the best balance of …

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Advanced measurement and diagnosis of the effect on the …

Tetrakis (ethylmethylamino) hafnium (TEMAHf) and ozone (O 3) were used to form the hafnium oxide layer at 350 °C. The gas pressure was 0.7 Torr. The gas pressure was 0.7 Torr.

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OPEN Numerical analysis of hafnium oxide and phase …

including food analysis, drug testing, and medical diagnostics. Because of its numerous advantages, SPR sensors ... and hafnium oxide (HfO 2)24–26. HfO2 is one such compound that has been the ...

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In Situ Gas Phase Diagnostics for Hafnium Oxide Atomic

Request PDF | In Situ Gas Phase Diagnostics for Hafnium Oxide Atomic Layer Deposition | Atomic layer deposition (ALD) is an important method for depositing the nanometer-scale, conformal high κ ...

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Silicon nanowires with high-k hafnium oxide dielectrics for …

High-k dielectrics, such as hafnium oxide (HfO(2)), have the known ability to address these challenges by passivating the exposed surfaces against destabilizing concerns of ion transport. With these fundamental stability issues addressed, a promising target for POC diagnostics and SiNWFETs has been small oligonucleotides, more specifically ...

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Hafnium (Hf) – Definition, Preparation, Properties, Uses

It is known for its high melting point and the ability to form complex compounds, such as hafnium oxide (HfO₂), which is used in insulating layers in semiconductors. ... Nuclear Medicine: Isotopes of hafnium may have applications in nuclear medicine, particularly in diagnostic imaging and radiation therapy. Research and Development: Hafnium ...

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Evaluation of hafnium oxide nanoparticles imaging …

This research aimed to compare the quantitative imaging attributes of synthesized hafnium oxide nanoparticles (NPs) derived from UiO-66-NH2(Hf) and two gadolinium- and …

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Crystal and Electronic Structure of Oxygen Vacancy …

synapses.2,5,6 Hafnium oxide was previously investigated and optimized as a high-k solution for semiconductor manufactur-ing. Therefore, its complementary metal oxide semiconductor (CMOS) compatibility is already well established.7−9 One key parameter that crucially affectsthe functionality of such oxide-based devices is oxygen deficiency ...

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Hafnia (HfO2) nanoparticles as an X-ray contrast agent and …

The interaction of hafnium oxide (HfO2) nanoparticles (NPs) with X-ray and mid-infrared radiation was investigated to assess the potential as a multifunctional diagnostic probe for X-ray computed tomography (CT) and/or mid-infrared biosensing. HfO2 NPs of controlled size were prepared by a sol-gel p …

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Effect of oxygen plasma treatment on the properties of ALD hafnium …

DOI: 10.1016/j.surfin.2024.105403 Corpus ID: 273893826; Effect of oxygen plasma treatment on the properties of ALD hafnium oxide films @article{Bulyarskiy2024EffectOO, title={Effect of oxygen plasma treatment on the properties of ALD hafnium oxide films}, author={Sergey V. Bulyarskiy and Kristina I. Litvinova and Grigory A. Rudakov and Anastasia A. Shibalova and …

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Hafnium Oxide (HfO2) – A Multifunctional Oxide: A Review …

Ferroelectric behavior modeled by Landau theory; a) Free energy F variation with polarization P according to Equation (1); the paraelectric phase exists at T > TC (red), and the ferroelectric ...

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